Immunology
Characterize Cell Types, Immune Repertoires, and Mechanisms of Immune Evasion at the Highest Resolution
Research into our complex and dynamic defense system benefits immensely from the latest developments in genomic measurement technologies. At Life Seq Data, we apply advanced computational analyses to high-throughput data, helping answer critical questions about the immune system and its role in health and disease.
Exploring the Immune System:
Discover Cell Types Understanding the composition and functions of the immune system often relies on transcriptomic and epigenomic sequencing. Our services include:
- Identification and Quantification: Analyze RNA-sequencing, single-cell RNA-sequencing, and single-cell ATAC sequencing data to identify, quantify, and compare immune cell types across developmental stages, niches, and conditions.
- Pathway Characterization: Characterize the intracellular pathways of immune cells in response to various stimulations.
- Cell Interactions: Identify interactions between immune cells and between immune cells and other tissues.
Characterize Immune Repertoires Targeted immune sequencing approaches are used to study the repertoire of lymphocyte receptors across different conditions or before and after infection or vaccination. By combining these data with single-cell RNA-seq, we can associate gene expression with clonal identities.
Uncover Host-Pathogen Interactions RNA-sequencing of immune cells from pathogen-infected models, whether in vivo or in vitro, allows for:
- Mechanism Characterization: Characterize how various immune cell types react to antigens, relay information, and neutralize pathogens.
Study Tumor Immune Evasion In cancer research, single-cell RNA-sequencing of tumors helps in:
- Immune Microenvironment Analysis: Characterize the immune microenvironments of tumors, identifying tumor-infiltrating immune cells to study immune evasion mechanisms and therapeutic opportunities.
- Neo-Antigen Identification: Use tumor RNA- or DNA-sequencing data to identify potential neo-antigens for cancer vaccine development.
Why Choose Life Seq Data?
- Advanced Technologies: We utilize the latest genomic measurement technologies for precise and high-resolution data analysis.
- Expertise in Immunology: Our team has extensive experience in immunology, immunobiology, and immuno-oncology, providing comprehensive insights into the immune system.
- Customized Analyses: Tailored computational analyses to meet the specific needs of your research projects.
- Collaborative Support: We work closely with you to understand your research goals and provide personalized support to achieve meaningful results.
Learn more about our expertise and typical computational analyses in immunology, immunobiology, and immuno-oncology. If you would like to benefit from our bioinformatics support, leave us a message, and we will arrange a call with one of our bioinformaticians.